- Kega Fusion: This emulator is compatible with Windows, macOS, and Linux. It can run Sega Genesis, Sega CD, and Sega Master System games.
- Gens: This emulator is designed specifically for Windows and can run Sega Genesis and Sega CD games.
- Mednafen: This emulator is available for Windows, macOS, and Linux. It supports Sega Genesis, Sega CD, and Sega Saturn games.
- Yaba Sanshiro: This emulator is compatible with Windows, macOS, and Linux. It can run Sega Saturn games.
- Redream: This emulator is available for Windows, macOS, and Linux. It can run Sega Dreamcast games.
- Genesis Plus GX: This emulator is available for Windows, macOS, and Linux. It can run Sega Genesis, Sega CD, and Sega Master System games.
- BlastEm: This emulator is designed specifically for Windows and can run Sega Genesis games.
- Higan: This emulator is available for Windows, macOS, and Linux. It can run Sega Genesis, Sega CD, and Sega Master System games, as well as games for several other consoles.
- MAME: MAME stands for Multiple Arcade Machine Emulator and is available for Windows, macOS, and Linux. It is primarily designed for arcade games but can also run some Sega arcade games.
- DEmul: This emulator is compatible with Windows and can run Sega Dreamcast, Sega NAOMI, and Sega Hikaru games.
Compare this page with the retro emulator and game-file guide before deciding what to use. Browse retro game guides for platform-specific reading.